Protein Engineering Research Group of Prof. Schwaneberg
at Jacobs University Bremen
Welcome!
MissionThe Schwaneberg Group seeks to be at the research frontier in the interdisciplinary field of directed protein evolution by developing novel methods for generating diversity at the gene level, analyzing consequence of mutational biases on the protein level and developing novel high-throughput screening systems that will ultimately lead to tailored-biocatalysts for significant applications in industry. We train our students in the cutting edge technologies of laboratory evolution, biocatalyst engineering and high throughput screening methodologies. We believe in integrating fundamental principles of protein design with environmental awareness in our research and seek to promote international scientific collaborations. We are experts in biocatalyst engineering with a focus on directed protein evolution. We are developing
Based on our core competences in directed protein evolution we apply our methods for
Based on our mutagenesis, statistical tools and high-throughput screening systems we collaborate extensively with companies (e.g. BASF AG, BRAIN AG; 9 signed secrecy agreements) and research groups with complementary expertise in large scale bioconversions, polymer chemistry, biofuel cell design and crystallography located in Bremen, Dortmund, Hamburg, Frankfurt, Basel and Austin (Texas, USA). With our technologies we aim to understand structure-function relationships of mainly oxidoreductases and to solve significant problems in industrial biocatalysis (see Mission Statement). Interested in joining our team as internship student, master course student, PhD or Post-doc? Click here for options. Based on our diversity methods and screening systems we will establish a company named SeSaM-Biotech in October 2007. SeSaM-Biotech will offer complete directed evolution services for costumers and develop mutagenesis kits for researchers. The first mutagenesis kit will be a unique transversion biased mutagenesis kit since transversions result in contrast to transitions in chemically "different" amino acid substitutions. Recent Research Highlights
Technology transfer highlight
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